Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.50 |
| ▸ | PI4KA | P42356 | 3/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 4/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489576 | 0.93 | ADORA2A (0.52) | CTSLADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL3125120 | 0.84 | TP53 (0.50) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL12157544 | 0.81 | TP53 (0.49) | CTSLADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL11488562 | 0.80 | ADORA2A (0.50) | CTSLADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL11360463 | 0.79 | ADORA2A (0.57) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11488384 | 0.78 | ADORA2A (0.60) | CTSLADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL11457082 | 0.78 | ADORA2A (0.58) | CTSLADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL11454848 | 0.77 | ADORA2A (0.58) | CTSLADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL6817943 | 0.76 | CDK2 (0.74) | FLT3SRCCDK1CDK2PDGFRA | |
| SCHEMBL6817936 | 0.76 | CDK2 (0.74) | FLT3SRCCDK1CDK2PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3336089-A1 | PURINE DERIVATIVES FOR USE IN THE TREATMENT OF ALLERGIC, INFLAMMATORY AND INFECTIOUS DISEASES | GlaxoSmithKline LLC (US) | 2018-06-20 | — | — | EP | disclosed |
| US-4232155-A | NONADRENERGIC BRONCHODILATOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1980-11-04 | — | — | US | disclosed |