Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.60 |
| ▸ | PI4KA | P42356 | 3/20 | 0.57 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.57 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.57 |
| ▸ | CDK2 | P24941 | 7/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.56 |
| ▸ | CDK1 | P06493 | 4/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.56 |
| ▸ | CDK4 | P11802 | 3/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.56 |
| ▸ | CCND1 | P24385 | 3/20 | 0.56 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.56 |
| ▸ | FLT3 | P36888 | 5/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487749 | 0.82 | ADORA2A (0.53) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2954550 | 0.80 | ADORA2A (0.66) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11489576 | 0.80 | ADORA2A (0.52) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13086149 | 0.79 | ADORA2A (0.65) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL17352601 | 0.79 | ADORA2A (0.65) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11488563 | 0.78 | CTSL (0.53) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11488562 | 0.78 | ADORA2A (0.50) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10763696 | 0.78 | ADORA2A (0.62) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30904621 | 0.78 | FLT3 (0.50) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11807186 | 0.77 | ADORA2A (0.63) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4232155-A | NONADRENERGIC BRONCHODILATOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1980-11-04 | — | — | US | claimed |
| US-4232155-A | NONADRENERGIC BRONCHODILATOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1980-11-04 | — | — | US | disclosed |