Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764121 | 0.74 | MAPK1 (0.36) | MAPK1HSD17B10CTNNB1WNT3A | |
| SCHEMBL8930182 | 0.74 | MAPK1 (0.39) | MAPK1HSD17B10CTNNB1WNT3A | |
| SCHEMBL11639802 | 0.67 | FOLH1 (0.32) | — | |
| SCHEMBL8930162 | 0.62 | — | — | |
| SCHEMBL8930221 | 0.62 | HSD17B10 (0.35) | MAPK1HSD17B10 | |
| SCHEMBL9173258 | 0.62 | ALDH1A1 (0.35) | — | |
| SCHEMBL12835333 | 0.62 | HCAR2 (0.31) | — | |
| SCHEMBL8929974 | 0.62 | MAPK1 (0.32) | MAPK1HSD17B10 | |
| SCHEMBL6143781 | 0.61 | MAPK1 (0.35) | MAPK1HSD17B10 | |
| SCHEMBL13005846 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4220646-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS, HYPNOTIC AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1980-09-02 | — | — | US | disclosed |
| US-4131674-A | TRANQUILIZERS, HYPNOTICS, ANTICONVULSANTS, ANTISPASMODICS | RHONE-POULENC INDUSTRIES (FR) | 1978-12-26 | — | — | US | disclosed |
| US-4086348-A | 2-(1,8-NAPHTHYRIDIN-2-YL)-3-AMINOCARBONYLOXYISOINOLIN-1-ONES; TRANQUILIZERS, HYPNOTICS, ANTICONVULSANTS, ANTISPASMODICS | RHONE-POULENC INDUSTRIES (FR) | 1978-04-25 | — | — | US | disclosed |