Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.67 |
| ▸ | SCN5A | Q14524 | 8/20 | 0.60 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13687352 | 0.86 | MAPK14 (0.58) | MAPK14SCN5AKDM4EALDH1A1HPGD | |
| SCHEMBL11165543 | 0.85 | MAPK14 (0.52) | MAPK14SCN5AMETRETPIM1 | |
| SCHEMBL11158736 | 0.84 | MAPK14 (0.51) | MAPK14SCN5AMETRETPIM1 | |
| SCHEMBL5773810 | 0.81 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL11158713 | 0.81 | SCN5A (0.65) | MAPK14SCN5AMETRETPIM1 | |
| SCHEMBL11472924 | 0.81 | SCN5A (0.63) | MAPK14SCN5AMETRETPIM1 | |
| SCHEMBL5765239 | 0.80 | MAPK14 (0.53) | MAPK14SCN5AHPGD | |
| SCHEMBL11159446 | 0.79 | MAPK14 (0.53) | MAPK14SCN5AMETRETPIM1 | |
| SCHEMBL11415066 | 0.78 | SCN5A (0.61) | MAPK14SCN5ARETPIM1FGFR1 | |
| SCHEMBL11162950 | 0.78 | MAPT (0.47) | MAPK14SCN5AMETRETPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242515-A | Substituted 3-alkyl-6-phenyl-1,2,4-triazolo-[4,3-a]pyridines | AMERICAN CYANAMID COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| EP-0017438-A1 | Substituted 3-alkyl-6-phenyl-1,2,4-triazolo(4,3-a)pyridines, processes for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1980-10-15 | — | — | EP | disclosed |