Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24003252 | 0.77 | PIM1 (0.40) | ALDH1A1MAPTHCRTR1LMNAPOLB | |
| SCHEMBL8894268 | 0.75 | LIMK1 (0.65) | LIMK1CDK5CDK5R1LMNAPOLB | |
| SCHEMBL11477966 | 0.75 | CLK1 (0.49) | LIMK1MAPTLMNAL3MBTL1EGFR | |
| SCHEMBL24003242 | 0.75 | CYP1A2 (0.33) | ALDH1A1MAPTHCRTR1LMNAPOLB | |
| SCHEMBL15766397 | 0.73 | LIMK1 (0.45) | LIMK1CDK5CDK5R1GPR3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2495354 | 0.71 | HRH4 (0.52) | LIMK1CDK5CDK5R1GPR3ALDH1A1 | |
| SCHEMBL11479791 | 0.70 | LIMK1 (0.52) | LIMK1ALDH1A1MAPTALOX5LMNA | |
| SCHEMBL25462165 | 0.69 | KDM4E (0.40) | LIMK1CDK5CDK5R1MAPTL3MBTL1 | |
| SCHEMBL25462168 | 0.69 | RAB9A (0.38) | LIMK1CDK5CDK5R1ALDH1A1ALOX15 | |
| SCHEMBL25462167 | 0.67 | LIMK1 (0.38) | LIMK1CDK5CDK5R1MAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239887-A | ANTIALLERGENS | USV PHARMACEUTICAL CORPORATION (US) | 1980-12-16 | — | — | US | disclosed |