Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422589 | 0.84 | MAPT (0.53) | KMT2AMEN1NPC1RAB9ATNF | |
| SCHEMBL27664158 | 0.79 | KMT2A (0.61) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL29462647 | 0.79 | KMT2A (0.49) | KMT2AMEN1NPC1RAB9ATNF | |
| SCHEMBL124710 | 0.79 | KMT2A (0.49) | KMT2AMEN1NPC1RAB9ATNF | |
| SCHEMBL6113261 | 0.79 | KMT2A (0.49) | KMT2AMEN1NPC1RAB9ATNF | |
| SCHEMBL29004329 | 0.79 | KMT2A (0.61) | KMT2AMEN1MAPTTHRBCYP1A2 | |
| SCHEMBL158111 | 0.77 | TDP1 (0.57) | KMT2AMEN1MAPT | |
| SCHEMBL8527590 | 0.77 | KMT2A (0.48) | KMT2AMEN1NPC1RAB9ATNF | |
| SCHEMBL91846 | 0.77 | MAPT (0.45) | KMT2AMAPTPTK2BRXFP1CYP1A2 | |
| SCHEMBL13384882 | 0.77 | KMT2A (0.68) | KMT2AMEN1MAPTTHRBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4201790-A | VASCULAR ADRENERGIC BLOCKING AGENTS | MAY & BAKER LIMITED (GB) | 1980-05-06 | — | — | US | disclosed |