Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91851 | 0.87 | MAPT (0.44) | MAPTROCK1TP53CYP1A2CYP2C19 | |
| SCHEMBL91821 | 0.85 | MAPT (0.43) | MAPTROCK1CYP1A2CYP2C19FFAR1 | |
| SCHEMBL91819 | 0.84 | MAPT (0.37) | MAPTROCK1POLBTP53CYP1A2 | |
| SCHEMBL91859 | 0.82 | ALDH1A1 (0.37) | MAPTROCK1TP53CYP1A2CYP2C19 | |
| SCHEMBL91860 | 0.79 | MAPT (0.38) | MAPTROCK1POLBTP53CYP1A2 | |
| SCHEMBL8422589 | 0.79 | MAPT (0.53) | MAPTPTK2BRXFP1POLBTP53 | |
| SCHEMBL14732717 | 0.77 | KMT2A (0.58) | PTK2BRXFP1CYP1A2LMNAALDH1A1 | |
| SCHEMBL11489237 | 0.77 | KMT2A (0.45) | MAPTPTK2BRXFP1CYP1A2LMNA | |
| SCHEMBL30073152 | 0.76 | PRSS1 (0.48) | MAPTRXFP1CYP1A2LMNAALDH1A1 | |
| SCHEMBL14140195 | 0.76 | RXFP1 (0.47) | MAPTPTK2BRXFP1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7419706-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-09-02 | — | — | US | disclosed |