Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.35 |
| ▸ | ATIC | P31939 | 2/20 | 0.35 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.34 |
| ▸ | CD40 | P25942 | 2/20 | 0.33 |
| ▸ | CD40LG | P29965 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHAT | P28329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633176 | 0.81 | TTR (0.50) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL6629829 | 0.81 | TTR (0.46) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL1742117 | 0.78 | TTR (0.59) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL11491211 | 0.78 | SUMO2 (0.48) | MAPK1ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL29360969 | 0.77 | TTR (0.58) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL179823 | 0.77 | TTR (0.58) | TTRFABP4CCNA2CDK2MAPK14 | |
| Water SCHEMBL7765550 | 0.75 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL21240726 | 0.75 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL2984538 | 0.75 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL11347041 | 0.75 | TTR (0.61) | TTRCDK2AURKAAURKBATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019846-A2 | Tanning agents of the azo series, their preparation and their use in the simultaneous tanning and dyeing of leather, and preparations containing them | BAYER AG (DE) | 1980-12-10 | — | — | EP | disclosed |