Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.58 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | MELK | Q14680 | 1/20 | 0.43 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179823 | 1.00 | TTR (0.58) | TTRFABP4CCNA2CDK2MAPK14 | |
| Water SCHEMBL7765550 | 0.98 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL21240726 | 0.98 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL2984538 | 0.98 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| Sulfuric Acid SCHEMBL11169213 | 0.88 | TTR (0.47) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL1742117 | 0.85 | TTR (0.59) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL15172852 | 0.83 | CA2 (0.61) | TTRCDK2NR4A1AURKAAURKB | |
| SCHEMBL28065908 | 0.83 | AURKA (0.50) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL7027692 | 0.82 | AURKA (0.53) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL9614841 | 0.82 | TTR (0.50) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112639470-B | Diagnostic method for amyloid-related disease | 阿米罗伊迪亚瑞典股份公司 | 2025-02-25 | — | — | CN | claimed |
| WO-2024218102-A1 | MODIFICATION OF AROMATIC POLYMERS | PREFERE RESINS HOLDING GMBH (DE) | 2024-10-24 | — | — | WO | claimed |
| US-12076406-B2 | Conjugates for targeting and clearing aggregates | MEDIMMUNE LIMITED (GB) | 2024-09-03 | — | — | US | claimed |
| EP-3775884-B1 | METHOD FOR THE DIAGNOSIS OF AMYLOID-ASSOCIATED DISEASES | AMYLOIDIA SWEDEN AB (SE) | 2024-05-08 | — | — | EP | claimed |
| US-20220026446-A1 | METHOD FOR THE DIAGNOSIS OF AMYLOID-ASSOCIATED DISEASES | AMYLOIDIA SWEDEN AB (SE) | 2022-01-27 | — | — | US | claimed |
| CN-112639470-B | Diagnostic method for amyloid-related disease | 阿米罗伊迪亚瑞典股份公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119490453-A | Synthesis method of 10-hydroxybenzo [ H ] quinoline | 山西义诺新材料技术有限公司 | 2025-02-21 | — | — | CN | disclosed |
| WO-2024218102-A1 | MODIFICATION OF AROMATIC POLYMERS | PREFERE RESINS HOLDING GMBH (DE) | 2024-10-24 | — | — | WO | disclosed |
| WO-2024200622-A1 | NEW METAL FREE BISAZO GREY DYE COMPOUNDS | ARCHROMA IP GMBH (CH) | 2024-10-03 | — | — | WO | disclosed |
| US-12076406-B2 | Conjugates for targeting and clearing aggregates | MEDIMMUNE LIMITED (GB) | 2024-09-03 | — | — | US | disclosed |
| EP-3775884-B1 | METHOD FOR THE DIAGNOSIS OF AMYLOID-ASSOCIATED DISEASES | AMYLOIDIA SWEDEN AB (SE) | 2024-05-08 | — | — | EP | disclosed |
| EP-4136141-A2 | FLUORESCENCE QUENCHING IMMUNOSSAY | IDEXX Laboratories, Inc. (US) | 2023-02-22 | — | — | EP | disclosed |
| US-20220026446-A1 | METHOD FOR THE DIAGNOSIS OF AMYLOID-ASSOCIATED DISEASES | AMYLOIDIA SWEDEN AB (SE) | 2022-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12076406-B2 | Conjugates for targeting and clearing aggregates | FCGR2A, FCGR3B, FCGR1A | TTR 13/4885FABP4 1905/4885CCNA2 3961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.