Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 9/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11805833 | 0.93 | ALKBH5 (0.39) | ALKBH5CYP2C19MAPTKMT2AALDH1A1 | |
| SCHEMBL11493185 | 0.84 | KDM4E (0.35) | ALKBH5CYP2C19MAPTKMT2AALDH1A1 | |
| SCHEMBL11494743 | 0.84 | CYP2C19 (0.38) | ALKBH5CYP2C19MAPTKMT2AALDH1A1 | |
| SCHEMBL11638385 | 0.78 | CYP2C19 (0.38) | ALKBH5CYP2C19MAPTKMT2AALDH1A1 | |
| SCHEMBL9330453 | 0.77 | ALKBH5 (0.40) | ALKBH5CYP2C19MAPTKMT2AALDH1A1 | |
| SCHEMBL11494550 | 0.75 | CYP2C19 (0.38) | ALKBH5CYP2C19MAPTKMT2AALDH1A1 | |
| SCHEMBL11489800 | 0.75 | ALKBH5 (0.39) | ALKBH5CYP2C19MAPTKMT2AALDH1A1 | |
| SCHEMBL11494745 | 0.74 | KDM4E (0.39) | ALKBH5CYP2C19MAPTKMT2AALDH1A1 | |
| SCHEMBL11809310 | 0.74 | ALKBH5 (0.33) | ALKBH5 | |
| SCHEMBL11496040 | 0.72 | KDM4E (0.43) | MAPTALDH1A1KDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188489-A | Process for the production of 3-substituted amino-5-pyrazolones | FUJI PHOTO FILM CO., LTD. (JP) | 1980-02-12 | — | — | US | disclosed |