Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668684 | 0.90 | ADORA3 (0.44) | ADORA3MAPTRECQLGABRA1GABRA3 | |
| SCHEMBL11484269 | 0.89 | TSHR (0.37) | ADORA3MAPTRECQLGABRA1GABRA3 | |
| SCHEMBL11493510 | 0.89 | ADORA3 (0.34) | ADORA3MAPTRECQLGABRA1GABRA3 | |
| SCHEMBL11493503 | 0.89 | ADORA3 (0.34) | ADORA3MAPTRECQLGABRA1GABRA3 | |
| SCHEMBL11496387 | 0.89 | ADORA3 (0.34) | ADORA3MAPTRECQLGABRA1GABRA3 | |
| SCHEMBL11493714 | 0.88 | TSHR (0.36) | ADORA3MAPTRECQLGABRA1GABRA3 | |
| SCHEMBL11486374 | 0.86 | ADORA3 (0.34) | ADORA3MAPTRECQLGABRA1GABRA3 | |
| SCHEMBL11669036 | 0.86 | ADORA3 (0.34) | ADORA3MAPTRECQLGABRA1GABRA3 | |
| SCHEMBL11669108 | 0.81 | ADORA3 (0.43) | ADORA3MAPTRECQLGABRA1GABRA3 | |
| SCHEMBL11492314 | 0.81 | PIK3CD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4220646-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS, HYPNOTIC AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1980-09-02 | — | — | US | disclosed |