Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900046 | 0.74 | — | — | |
| SCHEMBL12285350 | 0.74 | LMNA (0.33) | LMNANOS1 | |
| SCHEMBL14964545 | 0.71 | JAK1 (0.36) | — | |
| SCHEMBL31030338 | 0.71 | LMNA (0.41) | LMNANOS1KDM4EMAPTRAB9A | |
| SCHEMBL31030400 | 0.71 | LMNA (0.41) | LMNANOS1KDM4EMAPTRAB9A | |
| SCHEMBL31030360 | 0.71 | LMNA (0.41) | LMNANOS1KDM4EMAPTRAB9A | |
| SCHEMBL11484372 | 0.71 | LMNA (0.41) | LMNANOS1KDM4EMAPTRAB9A | |
| SCHEMBL31030307 | 0.71 | LMNA (0.41) | LMNANOS1KDM4EMAPTRAB9A | |
| SCHEMBL2462529 | 0.71 | MAPT (0.40) | LMNANOS1KDM4EMAPTRAB9A | |
| SCHEMBL11342505 | 0.69 | LMNA (0.40) | LMNANOS1KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008056-A1 | N-substituted pyrazole derivatives, process for their preparation and N-hydroxyalkylpyrazoles obtained in the course of this process | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |