Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 17/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20658215 | 0.84 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL20658202 | 0.75 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL17026408 | 0.75 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL8568039 | 0.74 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL11542277 | 0.70 | — | — | |
| SCHEMBL19889812 | 0.70 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL2494844 | 0.69 | CA12 (0.33) | KCNH2 | |
| SCHEMBL11541959 | 0.69 | PTPN7 (0.43) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9729154 | 0.68 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL867084 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011608-A1 | Novel allenic amine and acid addition salts thereof, a process for their preparation, pharmaceutical preparations comprising them and the use of these compounds in the preparation of pharmaceutical compositions | Astra Läkemedel Aktiebolag (SE) | 1980-05-28 | — | — | EP | disclosed |