Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729408 | 0.92 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL20658215 | 0.81 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL240366 | 0.77 | TSHR (0.43) | KCNH2TSHR | |
| SCHEMBL19497014 | 0.75 | TSHR (0.42) | KCNH2TSHR | |
| SCHEMBL19999960 | 0.72 | TSHR (0.43) | KCNH2TSHR | |
| SCHEMBL17026408 | 0.72 | KCNH2 (0.53) | KCNH2TSHR | |
| SCHEMBL20658202 | 0.72 | KCNH2 (0.53) | KCNH2TSHR | |
| SCHEMBL19889812 | 0.71 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL8568039 | 0.71 | KCNH2 (0.43) | KCNH2 | |
| Acetonitrile SCHEMBL28917541 | 0.71 | TSHR (0.41) | KCNH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162360-A | Treating hypercholesterolemia and atherosclerosis; ACAT acyl-coenzyme A:-cholesterol acyltransferase | WARNER-LAMBERT COMPANY (US) | 1992-11-10 | — | — | US | disclosed |