Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28357093 | 0.88 | POLB (0.59) | FFAR1CES2CES1CNR2POLB | |
| SCHEMBL25033296 | 0.83 | SRD5A2 (0.57) | SRD5A2AKR1B1FFAR1ABCC4LMNA | |
| SCHEMBL27662594 | 0.81 | FFAR1 (0.73) | SRD5A2AKR1B1FFAR1CNR2POLB | |
| SCHEMBL27662443 | 0.81 | FFAR1 (0.73) | SRD5A2AKR1B1FFAR1CNR2POLB | |
| SCHEMBL4565148 | 0.81 | FFAR1 (0.73) | SRD5A2AKR1B1FFAR1CNR2POLB | |
| SCHEMBL8332028 | 0.78 | AKR1B1 (0.52) | SRD5A2AKR1B1FFAR1PPARGPPARA | |
| SCHEMBL11300169 | 0.78 | POLB (0.54) | SRD5A2AKR1B1FFAR1ABCC4LMNA | |
| SCHEMBL3485914 | 0.76 | SLC6A4 (0.41) | SRD5A2TSHRCES2CES1 | |
| SCHEMBL32660768 | 0.76 | SLC6A2 (0.58) | SRD5A2AKR1B1FFAR1ALOX15 | |
| SCHEMBL586226 | 0.75 | SMN1; SMN2 (0.51) | SRD5A2LMNAGAAHTTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190579-A | Synthesis of beta-lactams from azetidine carboxylic acid esters | RESEARCH CORPORATION (US) | 1980-02-26 | — | — | US | disclosed |