Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.43 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MPL | P40238 | 7/20 | 0.42 |
| ▸ | CTRC | Q99895 | 2/20 | 0.42 |
| ▸ | SLC7A11 | Q9UPY5 | 3/20 | 0.41 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490858 | 0.83 | MPL (0.50) | AURKAAURKBMEN1KMT2ASUMO2 | |
| SCHEMBL28963365 | 0.73 | KMT2A (0.49) | AURKAAURKBMEN1KMT2AESR1 | |
| SCHEMBL465006 | 0.72 | CDK2 (0.53) | AURKAAURKBMEN1KMT2AMPL | |
| Water SCHEMBL28963036 | 0.71 | KMT2A (0.47) | AURKAAURKBMEN1KMT2AESR1 | |
| SCHEMBL153735 | 0.70 | NT5E (0.59) | AURKAAURKBMEN1KMT2ASUMO2 | |
| SCHEMBL10354361 | 0.70 | CDK2 (0.51) | AURKAAURKBMEN1KMT2AMPL | |
| SCHEMBL1808445 | 0.70 | CDK2 (0.59) | AURKAAURKBMEN1KMT2AALDH1A1 | |
| SCHEMBL29608931 | 0.70 | AURKB (0.64) | AURKAAURKBMEN1KMT2ASUMO2 | |
| SCHEMBL156055 | 0.70 | AURKB (0.64) | AURKAAURKBMEN1KMT2ASUMO2 | |
| SCHEMBL15121285 | 0.70 | ESR1 (0.64) | AURKAAURKBMEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4212801-A | Unsymmetrical 1:2-chromium complexes containing an azo and an azomethine bond | BASF AKTIENGESELLSCHAFT (DE) | 1980-07-15 | — | — | US | disclosed |