Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 7/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | RAD51 | Q06609 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261741 | 0.82 | ADORA2A (0.49) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11493551 | 0.82 | MAPK8 (0.50) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11417540 | 0.81 | MAPK8 (0.55) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20816334 | 0.80 | RAD51 (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11493554 | 0.78 | MAPK8 (0.52) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11485503 | 0.78 | ABL1 (0.48) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11491311 | 0.77 | RECQL (0.49) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11492050 | 0.76 | ADORA2A (0.48) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11495421 | 0.76 | RAD51 (0.65) | MAPK8HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11487184 | 0.76 | HPGD (0.57) | MAPK8HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200750-A | ANTIINFLAMMATORY AGENTS, FUNGICIDES, ANTIBODY INHIBITORS | WESTWOOD PHARMACEUTICALS INC. (US) | 1980-04-29 | — | — | US | claimed |