Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 1.00 |
| ▸ | FFAR1 | O14842 | 2/20 | 1.00 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 1.00 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 5/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.75 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.75 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 6/20 | 0.57 |
| ▸ | PPARD | Q03181 | 6/20 | 0.57 |
| ▸ | PPARA | Q07869 | 6/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | FABP4 | P15090 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700807 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL506393 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| Sebacic Acid SCHEMBL17889405 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL8984594 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| Sebacic Acid SCHEMBL6060953 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL150421 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL28484 | 1.00 | — | — | |
| 1,5-Pentanediol SCHEMBL20696141 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL21114450 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL3503243 | 1.00 | GPR84 (1.00) | GPR84FFAR1FFAR4CAMK2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430785-A | Polyurethane pigment grinding dispersion resin and preparation method and application thereof | 黄山中泽新材料有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-116814212-A | Degradable moisture-cured polyurethane structural adhesive | 常州都铂高分子有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-102618204-B | Hot-melt adhesive for bonding layer of artificial leather and preparation method as well as application thereof | JIANGYIN NUOKE SCIENCE AND TECHNOLOGY CO LTD | 2013-11-27 | — | — | CN | claimed |
| CN-117430785-A | Polyurethane pigment grinding dispersion resin and preparation method and application thereof | 黄山中泽新材料有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-116814212-A | Degradable moisture-cured polyurethane structural adhesive | 常州都铂高分子有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-109791381-B | Electrophotographic photoreceptor, and electrophotographic process cartridge and image forming apparatus containing the same | 三菱化学株式会社 | 2023-03-10 | — | — | CN | disclosed |
| US-8545949-B2 | Resin composition, thermal transfer-receiving sheet, and method for making thermal transfer-receiving sheet | SONY CORPORATION (JP) | 2013-10-01 | — | — | US | disclosed |
| CN-102093660-B | Receptor layer forming composition and thermal transfer receiving sheet | SONY CORP | 2013-09-04 | — | — | CN | disclosed |
| CN-102093660-A | Receptor layer forming composition and thermal transfer receiving sheet | SONY CORP | 2011-06-15 | — | — | CN | disclosed |
| CN-101993578-A | Resin composition, thermal transfer-receiving sheet, and method for making thermal transfer-receiving sheet | SONY CORP | 2011-03-30 | — | — | CN | disclosed |
| US-20110045212-A1 | RESIN COMPOSITION, THERMAL TRANSFER-RECEIVING SHEET, AND METHOD FOR MAKING THERMAL TRANSFER-RECEIVING SHEET | SONY CORPORATION (JP) | 2011-02-24 | — | — | US | disclosed |