Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 8/20 | 0.44 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.41 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11768773 | 0.92 | LTB4R (0.48) | AKR1B1LTB4RKDM4EMEN1ALDH1A1 | |
| SCHEMBL11492240 | 0.91 | TTR (0.46) | AKR1B1LTB4RKDM4EMEN1ALDH1A1 | |
| SCHEMBL11766829 | 0.90 | LTB4R (0.56) | AKR1B1LTB4RKDM4EMEN1ALDH1A1 | |
| SCHEMBL11783285 | 0.90 | LTB4R (0.56) | AKR1B1LTB4RKDM4EMEN1ALDH1A1 | |
| SCHEMBL11767174 | 0.90 | LTB4R (0.56) | AKR1B1LTB4RKDM4EMEN1ALDH1A1 | |
| SCHEMBL11768768 | 0.90 | LTB4R (0.56) | AKR1B1LTB4RKDM4EMEN1ALDH1A1 | |
| SCHEMBL11767105 | 0.90 | TTR (0.48) | AKR1B1LTB4RKDM4EMEN1ALDH1A1 | |
| SCHEMBL11486075 | 0.88 | LTB4R (0.46) | AKR1B1LTB4RKDM4EMEN1ALDH1A1 | |
| SCHEMBL11768077 | 0.86 | AKR1B1 (0.49) | AKR1B1LTB4RKDM4EMEN1ALDH1A1 | |
| SCHEMBL11485969 | 0.85 | TTR (0.54) | AKR1B1LTB4RKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217361-A | Disubstituted xanthone-2-carboxylic acid antiallergy agents | SYNTEX (U.S.A.) INC. (US) | 1980-08-12 | — | — | US | disclosed |