Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11495484 | 1.00 | PEPD (0.41) | PEPDMEN1BLMKMT2AACE | |
| SCHEMBL11457006 | 1.00 | PEPD (0.41) | PEPDMEN1BLMKMT2AACE | |
| SCHEMBL11453674 | 0.95 | EPHX1 (0.40) | MEN1BLMKMT2AALDH1A1LMNA | |
| SCHEMBL11453672 | 0.95 | EPHX1 (0.40) | MEN1BLMKMT2AALDH1A1LMNA | |
| SCHEMBL11453673 | 0.95 | EPHX1 (0.40) | MEN1BLMKMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11467862 | 0.93 | PEPD (0.39) | PEPDALDH1A1LMNAEPHX1 | |
| Hydrochloric Acid SCHEMBL11467863 | 0.93 | PEPD (0.39) | PEPDALDH1A1LMNAEPHX1 | |
| Hydrochloric Acid SCHEMBL11467864 | 0.93 | PEPD (0.39) | PEPDALDH1A1LMNAEPHX1 | |
| SCHEMBL8207654 | 0.81 | PEPD (0.37) | PEPDMEN1BLMKMT2AACE | |
| SCHEMBL14597528 | 0.77 | EPHX1 (0.40) | ALDH1A1PKMEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4197308-A | Analgesic N-(2-heterocyclic-amino cycloaliphatic) benzamides | THE UPJOHN COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4098904-A | ANALGESIC N-(2-AMINOCYCLOALIPHATIC)BENZAMIDES | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |