Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457006 | 0.81 | PEPD (0.41) | PEPDMEN1BLMKMT2AACE | |
| SCHEMBL11495481 | 0.81 | PEPD (0.41) | PEPDMEN1BLMKMT2AACE | |
| SCHEMBL11495484 | 0.81 | PEPD (0.41) | PEPDMEN1BLMKMT2AACE | |
| SCHEMBL15731643 | 0.79 | EPHX1 (0.34) | — | |
| SCHEMBL283046 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL283047 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL284320 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL11453672 | 0.77 | EPHX1 (0.40) | MEN1BLMKMT2A | |
| SCHEMBL15223876 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL15223878 | 0.77 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033389-A2 | MACROCYCLIC HCV INHIBITORS AND THEIR USES | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |