SCHEMBL114961

SCHEMBL114961

O=S(=O)(O)c1ccc(O)c2ncccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
COMT P21964 6/20 1.00
FTO Q9C0B1 2/20 0.76
ALDH1A1 P00352 1/20 0.67
CYP1A2 P05177 1/20 0.67
ALOX15 P16050 1/20 0.67
HIF1A Q16665 1/20 0.67
HSD17B10 Q99714 1/20 0.67
MEN1 O00255 1/20 0.66
NSD2 O96028 1/20 0.66
POLB P06746 1/20 0.66
IDE P14735 1/20 0.66
DUSP3 P51452 1/20 0.66
CCR6 P51684 1/20 0.66
BLM P54132 1/20 0.66
KMT2A Q03164 1/20 0.66
KDM4E B2RXH2 4/20 0.62
GLO1 Q04760 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29456746 1.00 COMT (1.00) COMTFTOALDH1A1CYP1A2ALOX15
SCHEMBL9511337 0.98 COMT (0.97) COMTFTOALDH1A1CYP1A2ALOX15
Water SCHEMBL505393 0.98 COMT (0.97) COMTFTOALDH1A1CYP1A2ALOX15
SCHEMBL7151883 0.98 COMT (0.97) COMTFTOALDH1A1CYP1A2ALOX15
Water SCHEMBL10628327 0.98 COMT (0.97) COMTFTOALDH1A1CYP1A2ALOX15
SCHEMBL9407080 0.98 COMT (0.97) COMTFTOALDH1A1CYP1A2ALOX15
SCHEMBL7156190 0.98 COMT (0.97) COMTFTOALDH1A1CYP1A2ALOX15
SCHEMBL8847297 0.98 COMT (0.97) COMTFTOALDH1A1CYP1A2ALOX15
SCHEMBL1873349 0.98 COMT (0.97) COMTFTOALDH1A1CYP1A2ALOX15
SCHEMBL10728563 0.98 COMT (0.97) COMTFTOALDH1A1CYP1A2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1791 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747611-A1 OPTICAL ELECTRODE ANALYTE DETECTION SYSTEM AND METHODS OF USE Vital Biosciences Inc. (CA) 2026-05-27 EP claimed
CN-122061024-A Method and system for efficiently enriching and deeply purifying gallium from gallium-containing vanadium precipitate 昆明理工大学 2026-05-19 CN claimed
US-12630744-B2 Polishing compositions and methods of use thereof FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2026-05-19 US claimed
CN-122061023-A Method for selectively enriching gallium from gallium-containing vanadium precipitate 昆明理工大学 2026-05-19 CN claimed
CN-122011884-A Self-repairing/corrosion early warning dual-functional coating based on corrosion cathode micro-area environment response release 西南交通大学 2026-05-12 CN claimed
US-12533430-B2 Metal nuclide-loaded carbon microsphere (CMS), preparation method, and use thereof Chengdu New Radiomedicine Technology Co., Ltd. (CN) 2026-01-27 US claimed
EP-4653506-A1 CHEMICAL MECHANICAL POLISHING COMPOSITIONS AND METHODS OF USE THEREOF FUJIFILM Electronic Materials U.S.A, Inc. (US) 2025-11-26 EP claimed
EP-4642956-A1 ON-DEMAND NITRIC OXIDE GENERATION AND DELIVERY DEVICES Nanjing Novlead Biotechnology Co., Ltd. (CN) 2025-11-05 EP claimed
EP-4224144-B1 METHODS OF CALIBRATING A FLUORESCENCE-MEASURING INSTRUMENT FOR MEASURING LOW CONCENTRATIONS OF SOLUBLE MAGNESIUM ECOLAB USA INC (US) 2025-10-08 EP claimed
EP-4082580-B1 CARBON MICROBEAD LOADED WITH METAL NUCLIDE, PREPARATION METHOD, AND APPLICATION CHENGDU NEW RADIOMEDICINE TECH CO LTD (CN) 2025-09-10 EP claimed
EP-0061444-A4 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS. UNION OIL CO (US) 1983-02-04 EP claimed
EP-0061444-A1 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS. UNION OIL CO (US) 1982-10-06 EP claimed
WO-1982001364-A1 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS UNION OIL CO (US) 1982-04-29 WO claimed
US-4283379-A WASHING SOLUTION OF SOLUBILIZED VANADIUM, WATER SOLUBLE NONQUINONE AROMATIC COMPOUNDS, THIOCYANATE IONS, AND A CARBOXYLATE COMPLEXING AGENT UNION OIL COMPANY OF CALIFORNIA (US) 1981-08-11 US claimed
US-4243648-A CONVERSION TO HYDROPHOBIC SULFUR, OXIDATIVE REGENERATION UNION OIL COMPANY OF CALIFORNIA (US) 1981-01-06 US claimed
US-4155741-A Stable suspension system for microencapsulated flowable formulations, and method of preparing stable suspension of microcapsules STAUFFER CHEMICAL COMPANY (US) 1979-05-22 US claimed
US-4117013-A AMINES, QUATERNARY AMMONIUM COMPOUNDS, OLEFIN EPOXIDES, HYDROXYQUI(OLINES, AMINE PHENOXIDES, GLYCIDYL HALIDES AND ETHERS UNITED TECHNOLOGIES CORPORATION (US) 1978-09-26 US claimed
US-4022703-A Stabilization of hydrogen peroxide in acid baths for cleaning metals PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-05-10 US claimed
US-4009087-A N-HETERO AROMATIC, AND SULFOALKYL OR SULFOARYL SULFIDE M&T CHEMICALS INC. (US) 1977-02-22 US claimed
US-3982999-A LEUKEMIA KHARASCH JEROME A 1976-09-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533430-B2 Metal nuclide-loaded carbon microsphere (CMS), preparation method, and use thereof CPS1, SRM, NES COMT 250/4885FTO 551/4885ALDH1A1 1172/4885
US-12630744-B2 Polishing compositions and methods of use thereof ZAP70, PRKDC, PEAK1 COMT 1425/4885FTO 176/4885ALDH1A1 3505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.