Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004469 | 0.87 | GFER (0.36) | TP53THRBTSHRALDH1A1THRA | |
| SCHEMBL8076236 | 0.86 | TAAR1 (0.46) | TAAR1TP53THRBTSHRALDH1A1 | |
| SCHEMBL8077541 | 0.86 | THRB (0.52) | THRBLPLLIPGTSHRL3MBTL1 | |
| SCHEMBL7783395 | 0.85 | GRIN2D (0.42) | TAAR1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7783399 | 0.85 | GRIN2D (0.42) | TAAR1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6285109 | 0.85 | GFER (0.41) | TP53THRBTSHRALDH1A1THRA | |
| SCHEMBL8076095 | 0.85 | HDAC1 (0.45) | TAAR1TP53THRBTSHRALDH1A1 | |
| SCHEMBL8062345 | 0.83 | HDAC1 (0.47) | TAAR1TP53THRBTSHRALDH1A1 | |
| SCHEMBL8073321 | 0.83 | HDAC1 (0.47) | TAAR1TP53THRBTSHRALDH1A1 | |
| SCHEMBL8063277 | 0.83 | HDAC1 (0.47) | TAAR1TP53THRBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12545653-B2 | Compound as PPAR agonist and application thereof | USA Elixiria Biotech Inc. (US) | 2026-02-10 | — | — | US | disclosed |
| CN-114409680-B | PPAR agonists and uses thereof | 上海怡立舍生物技术有限公司 | 2023-11-21 | — | — | CN | disclosed |
| US-20230322692-A1 | COMPOUND AS PPAR AGONIST AND APPLICATION THEREOF | USA Elixiria Biotech Inc. (US) | 2023-10-12 | — | — | US | disclosed |
| US-11691953-B2 | Compound as PPAR agonist and application thereof | USA Elixiria Biotech Inc. | 2023-07-04 | — | — | US | disclosed |
| CN-114409680-A | PPAR agonist and application thereof | 上海怡立舍生物技术有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-108250058-B | PPAR agonists and their use in the treatment of Alzheimer's disease and other diseases | 上海怡立舍生物技术有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-111116285-B | Efficient preparation method of 1-aryl-4-butene compound | 大连理工大学 | 2021-05-07 | — | — | CN | disclosed |
| US-20200331868-A1 | COMPOUND AS PPAR AGONIST AND APPLICATION THEREOF | USA Elixiria Biotech Inc. | 2020-10-22 | — | — | US | disclosed |
| CN-111116285-A | Efficient preparation method of 1-aryl-4-butene compound | 大连理工大学 | 2020-05-08 | — | — | CN | disclosed |
| WO-2019141229-A1 | COMPOUND AS PPAR AGONIST AND APPLICATION THEREOF | 上海怡立舍生物技术有限公司 | 2019-07-25 | — | — | WO | disclosed |
| US-5466838-A | Catalytic reaction of olefin with oxygen in the presence of aldehyde | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-11-14 | — | — | US | disclosed |
| EP-0540009-B1 | Process for producing epoxides | SUMITOMO CHEMICAL CO (JP) | 1995-08-30 | — | — | EP | disclosed |
| US-5430117-A | Nonconjugated diene-vinyl aromatic-α-olefin interpolymers | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |
| EP-0634427-A1 | Higher alpha-olefin copolymer, process for the preparation of the same, rubber composition comprising the same, and rubber molded product comprising the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-01-18 | — | — | EP | disclosed |
| US-5367087-A | Process for producing epoxide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-11-22 | — | — | US | disclosed |
| EP-0540009-A1 | Process for producing epoxides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-5158949-A | 1,3-DIOXOLANE DERIVATIVES AS CHOLESTEROL-LOWERING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0492474-A1 | 1,3-Dioxolane derivatives as cholesterol-lowering agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| US-4287378-A | BY CATALYTIC DISPROPORTIONATION, PROPORTIONATION, OR ISOMERIZATION WHEREIN THE CATALYST IS A TRANSITION METAL OXIDE EXPOSED TO RADIATION | PHILLIPS PETROLEUM COMPANY (US) | 1981-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12545653-B2 | Compound as PPAR agonist and application thereof | PPARA, PPARD, PPARG | TAAR1 877/4885TP53 2749/4885THRB 29/4885 |
| US-11691953-B2 | Compound as PPAR agonist and application thereof | PPARA, PPARG, PPARD | TAAR1 988/4885TP53 3507/4885THRB 636/4885 |
| US-20200331868-A1 | COMPOUND AS PPAR AGONIST AND APPLICATION THEREOF | PPARA, PPARG, PPARD | TAAR1 988/4885TP53 3507/4885THRB 636/4885 |
| US-20230322692-A1 | COMPOUND AS PPAR AGONIST AND APPLICATION THEREOF | PPARA, PPARG, PPARD | TAAR1 988/4885TP53 3507/4885THRB 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.