Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PDE4A | P27815 | 7/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 3/20 | 0.49 |
| ▸ | BRD2 | P25440 | 2/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.49 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11394726 | 0.84 | MEN1 (0.80) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL11399416 | 0.83 | MEN1 (0.78) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL11395669 | 0.83 | MEN1 (0.78) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL9123054 | 0.83 | MAPK1 (0.65) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL11401591 | 0.81 | MEN1 (0.81) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL7519416 | 0.81 | PDE4A (0.56) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL11442061 | 0.79 | RXFP1 (0.71) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL11460096 | 0.78 | MEN1 (0.65) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL11496625 | 0.78 | RXFP1 (0.69) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL1713301 | 0.77 | MEN1 (0.71) | ALDH1A1MEN1KMT2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289776-A | VASODILATORS, FIBRINOLYTIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-15 | — | — | US | disclosed |