Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.81 |
| ▸ | PDE4A | P27815 | 8/20 | 0.76 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.76 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.76 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.76 |
| ▸ | BRD4 | O60885 | 3/20 | 0.72 |
| ▸ | BRD2 | P25440 | 2/20 | 0.72 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.72 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.72 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11394726 | 0.97 | MEN1 (0.80) | MEN1KMT2AALDH1A1PDE4APDE4B | |
| SCHEMBL11399416 | 0.95 | MEN1 (0.78) | MEN1KMT2AALDH1A1PDE4APDE4B | |
| SCHEMBL11395669 | 0.95 | MEN1 (0.78) | MEN1KMT2AALDH1A1PDE4APDE4B | |
| SCHEMBL7457891 | 0.90 | MEN1 (1.00) | MEN1KMT2AALDH1A1PDE4APDE4B | |
| SCHEMBL7326739 | 0.88 | MEN1 (0.77) | MEN1KMT2AALDH1A1PDE4APDE4B | |
| SCHEMBL11399596 | 0.88 | MEN1 (0.95) | MEN1KMT2AALDH1A1PDE4APDE4B | |
| SCHEMBL19066317 | 0.84 | BRD4 (1.00) | MEN1KMT2AALDH1A1PDE4APDE4B | |
| SCHEMBL7031729 | 0.84 | MEN1 (0.87) | MEN1KMT2AALDH1A1PDE4APDE4B | |
| SCHEMBL11456819 | 0.82 | PDE4A (0.77) | MEN1KMT2AALDH1A1PDE4APDE4B | |
| SCHEMBL11497052 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289776-A | VASODILATORS, FIBRINOLYTIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-15 | — | — | US | disclosed |