SCHEMBL11501209

SCHEMBL11501209

C=C(N)CN1CCC(=O)N1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.43
ALOX5 P09917 5/20 0.34
TSHR P16473 1/20 0.32
G6PD P11413 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16611743 0.73
SCHEMBL5490909 0.73
SCHEMBL8065127 0.69
Bromide SCHEMBL8075029 0.69 GAA (0.47) GAAALOX5G6PDALOX15ALOX12
SCHEMBL10330565 0.69
SCHEMBL6565391 0.68
SCHEMBL12763758 0.64 GAA (0.46) GAAALOX5TSHRG6PDALOX15
SCHEMBL22446137 0.63 TSHR (0.69) TSHRALDH1A1
SCHEMBL6429311 0.63 POLB (0.41) ALDH1A1MAPT
SCHEMBL7390893 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4228230-A Ultrasonic imaging of internally fogged silver halide elements EASTMAN KODAK COMPANY (US) 1980-10-14 US disclosed
EP-0013652-A2 Ultrasonographic process EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-07-23 EP disclosed