Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.59 |
| ▸ | CNR2 | P34972 | 9/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474154 | 0.88 | CNR2 (0.62) | CNR1CNR2NR1I2ADORA3SLC6A3 | |
| SCHEMBL11578292 | 0.88 | CNR2 (0.62) | CNR1CNR2NR1I2ADORA3SLC6A3 | |
| SCHEMBL11578289 | 0.88 | CNR2 (0.62) | CNR1CNR2NR1I2ADORA3SLC6A3 | |
| SCHEMBL31545582 | 0.86 | CNR2 (0.66) | CNR1CNR2NR1I2 | |
| SCHEMBL31545090 | 0.83 | CNR2 (0.71) | CNR1CNR2NR1I2 | |
| SCHEMBL29407185 | 0.83 | CNR2 (0.71) | CNR1CNR2NR1I2 | |
| SCHEMBL13280342 | 0.83 | CNR2 (0.71) | CNR1CNR2NR1I2 | |
| SCHEMBL16781742 | 0.83 | CNR2 (0.71) | CNR1CNR2NR1I2 | |
| SCHEMBL22787424 | 0.83 | CNR2 (0.71) | CNR1CNR2NR1I2 | |
| SCHEMBL31545008 | 0.79 | CNR1 (0.58) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4232018-A | TRANQUILIZERS; NONHABIT-FORMING | PFIZER INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4209520-A | Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents | PFIZER INC. (US) | 1980-06-24 | — | — | US | disclosed |
| US-4133819-A | Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents | PFIZER INC. (US) | 1979-01-09 | — | — | US | disclosed |