Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RRM1 | P23921 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243062 | 0.81 | NPC1 (0.49) | RAB9ANPC1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL28247865 | 0.81 | NPC1 (0.71) | RAB9ANPC1KDM4EALDH1A1RRM1 | |
| SCHEMBL11501148 | 0.80 | CYP1A2 (0.51) | RAB9ANPC1ALDH1A1GAAKMT2A | |
| SCHEMBL23706458 | 0.79 | NPC1 (1.00) | RAB9ANPC1KDM4EALDH1A1CASP3 | |
| SCHEMBL9338070 | 0.79 | CYP2D6 (0.48) | RAB9ANPC1KDM4EALDH1A1GFER | |
| SCHEMBL11829001 | 0.79 | SMN1; SMN2 (0.53) | RAB9ANPC1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11835607 | 0.78 | NPC1 (0.59) | RAB9ANPC1KDM4EALDH1A1CASP3 | |
| SCHEMBL11135564 | 0.78 | NPC1 (0.68) | RAB9ANPC1KDM4EALDH1A1RRM1 | |
| SCHEMBL5173798 | 0.77 | ALDH1A1 (0.54) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL9617869 | 0.75 | CYP2D6 (0.43) | RAB9AKDM4EALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |