Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | FPR3 | P25089 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322214 | 0.76 | HRH3 (0.47) | KDM4ECARM1PRMT6PRMT8LTA4H | |
| SCHEMBL9322304 | 0.75 | CARM1 (0.41) | KDM4EALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL15901425 | 0.75 | HRH3 (0.43) | KDM4EALDH1A1LTA4HHRH3GNAI3 | |
| SCHEMBL21730510 | 0.74 | HRH3 (0.44) | KDM4EALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL21730428 | 0.74 | HRH3 (0.44) | KDM4EALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL21730429 | 0.73 | USP2 (0.44) | KDM4EALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL20979276 | 0.73 | CARM1 (0.39) | KDM4EALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL27801521 | 0.73 | EPHX1 (0.42) | ALDH1A1GNAI3GNAO1GNAI1TSHR | |
| SCHEMBL1677697 | 0.72 | KDM4E (0.53) | KDM4EALDH1A1CARM1PRMT6PRMT8 | |
| SCHEMBL13160710 | 0.72 | HRH3 (0.54) | KDM4EALDH1A1CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4212866-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIEDEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-07-15 | — | — | US | disclosed |