Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259474 | 0.78 | CASP3 (0.44) | MEN1KMT2AALDH1A1LMNATP53 | |
| SCHEMBL2639666 | 0.74 | DNMT1 (0.46) | DNMT1ADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL10426593 | 0.72 | DNMT1 (0.50) | DNMT1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL5022469 | 0.71 | CASP3 (0.54) | DNMT1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL8407062 | 0.68 | DNMT1 (0.50) | DNMT1ADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL4109839 | 0.68 | DNMT1 (0.50) | DNMT1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL567138 | 0.68 | DNMT1 (0.50) | DNMT1MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL4104478 | 0.68 | DNMT1 (0.50) | DNMT1ADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL6734024 | 0.68 | DNMT1 (0.50) | DNMT1ADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL5742513 | 0.68 | KMT2A (0.59) | DNMT1MEN1KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204063-A | ANTITUMOR AGENTS | LABORATORIOS MADE, S.A. (ES) | 1980-05-20 | — | — | US | disclosed |