Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843033 | 0.95 | — | — | |
| SCHEMBL2749936 | 0.95 | CYP3A4 (0.32) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL10584467 | 0.90 | CYP3A4 (0.30) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL85365 | 0.86 | MEN1 (0.31) | — | |
| SCHEMBL11751623 | 0.86 | — | — | |
| SCHEMBL1004841 | 0.84 | CYP3A4 (0.32) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL31831117 | 0.80 | MEN1 (0.33) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL1006950 | 0.80 | MEN1 (0.33) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL2869098 | 0.79 | HPGD (0.37) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL631112 | 0.76 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528140-B2 | Substituted pyrrolo[3,2-d]pyrimidines as glycogen synthase kinase (GSK) inhibitors | TEIJIN LIMITED (JP) | 2009-05-05 | — | — | US | disclosed |
| US-7528140-B2 | Substituted pyrrolo[3,2-d]pyrimidines as glycogen synthase kinase (GSK) inhibitors | TEIJIN LIMITED (JP) | 2009-05-05 | — | — | US | disclosed |
| US-4169790-A | Solid surface texture suitable for a stationary phase for chromatography | SOUTH AFRICAN INVENTIONS DEVELOPMENT CORPORATION (ZA) | 1979-10-02 | — | — | US | disclosed |
| US-4034007-A | Process for the production of halogenated aromatic carboxylic acids | TENNECO CHEMICALS, INC. (US) | 1977-07-05 | — | — | US | disclosed |