Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573466 | 0.89 | EPHX2 (0.45) | EPHX2EPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL11572183 | 0.82 | EPHX2 (0.44) | KMT2AEPHX2EPHX1HDAC3HDAC4 | |
| SCHEMBL11571508 | 0.81 | EPHX2 (0.44) | KMT2AEPHX2EPHX1KDM4E | |
| Hydrochloric Acid SCHEMBL11501893 | 0.81 | KDM4E (0.45) | KMT2AEPHX2EPHX1KDM4E | |
| SCHEMBL11573439 | 0.79 | KDM4E (0.45) | KMT2AEPHX2EPHX1KDM4E | |
| SCHEMBL11572781 | 0.78 | ALDH1A1 (0.39) | KMT2ASMN1; SMN2OPRK1EPHX2EPHX1 | |
| SCHEMBL11573353 | 0.73 | KMT2A (0.39) | KMT2ASMN1; SMN2EPHX2EPHX1HTT | |
| SCHEMBL3081626 | 0.70 | EPHX2 (0.47) | KMT2ASMN1; SMN2EPHX2EPHX1HTT | |
| SCHEMBL11501583 | 0.69 | EPHX2 (0.47) | EPHX2HTT | |
| SCHEMBL4017279 | 0.68 | EPHX2 (0.66) | EPHX2HDAC3HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | claimed |
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | disclosed |