SCHEMBL11501648

SCHEMBL11501648

C=C(Cl)C(=C)Cl.C=CC(=C)C

nearest known ligand 0.71

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.71
TSHR P16473 2/20 0.71
TP53 P04637 1/20 0.71
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,1-Dichloroethene SCHEMBL10879205 0.89
Chloroprene SCHEMBL302230 0.86 ALDH1A1 (0.71) ALDH1A1TSHRTP53HSD17B10TDP1
SCHEMBL20661241 0.84 ALDH1A1 (1.00) ALDH1A1TSHRTP53HSD17B10TDP1
SCHEMBL1331930 0.84
SCHEMBL322832 0.84 ALDH1A1 (1.00) ALDH1A1TSHRTP53HSD17B10TDP1
SCHEMBL14855 0.84
Vinyl Chloride SCHEMBL678992 0.81
SCHEMBL7091146 0.81
Charcoal, Activated SCHEMBL318468 0.81
SCHEMBL4421781 0.81 ALDH1A1 (0.91) ALDH1A1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4146592-A BLEND OF CROSSLINKED AND UNCROSSLINKED DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1979-03-27 US disclosed
US-3933754-A CROSSLINKED WITH DIMETHACRYLATES, DIVINYLBENZENE OR DIALLYL PHTHALATE DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-01-20 US disclosed