SCHEMBL1150263

SCHEMBL1150263

CCCCOC(=O)[C@H]1[C@H](C=O)C1(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
ATM Q13315 1/20 0.43
ALDH1A1 P00352 1/20 0.41
TSHR P16473 4/20 0.41
HPGD P15428 1/20 0.41
HCAR2 Q8TDS4 3/20 0.39
NAAA Q02083 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ESR1 P03372 2/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MAPK1 P28482 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL357783 1.00 LMNA (0.49) LMNAATMALDH1A1TSHRHPGD
SCHEMBL1150261 1.00 LMNA (0.49) LMNAATMALDH1A1TSHRHPGD
SCHEMBL1149789 0.95 LMNA (0.47) LMNAATMALDH1A1TSHRHPGD
SCHEMBL1149793 0.95 LMNA (0.47) LMNAATMALDH1A1TSHRHPGD
SCHEMBL1149791 0.95 LMNA (0.47) LMNAATMALDH1A1TSHRHPGD
SCHEMBL2126033 0.94 LMNA (0.46) LMNAALDH1A1TSHRHCAR2NAAA
SCHEMBL2127665 0.94 LMNA (0.46) LMNAALDH1A1TSHRHCAR2NAAA
SCHEMBL2128181 0.94 LMNA (0.46) LMNAALDH1A1TSHRHCAR2NAAA
SCHEMBL1150644 0.94 LMNA (0.46) LMNAALDH1A1TSHRHCAR2NAAA
SCHEMBL1150645 0.94 LMNA (0.46) LMNAALDH1A1TSHRHCAR2NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7893294-B2 Process for production of trans-2, 2-dimethyl-3-formylcyclopropanecarboxylic acid ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-22 US disclosed
US-20090314987-A1 PROCESS FOR PRODUCTION OF TRANS-2, 2-DIMETHYL-3-FORMYLCYCLOPROPANECARBOXYLIC ACID ESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-12-24 US disclosed
EP-2053037-A1 PROCESS FOR PRODUCTION OF TRANS-2,2-DIMETHYL- 3-FORMYLCYCLOPROPANE CARBOXYLIC ACID ESTER Sumitomo Chemical Company, Limited (JP) 2009-04-29 EP disclosed