Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | BAX | Q07812 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11792902 | 0.92 | HRH1 (0.63) | HRH1TSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL791816 | 0.92 | HRH1 (0.63) | HRH1TSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1829827 | 0.89 | HRH1 (0.65) | HRH1TSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL796490 | 0.85 | HRH1 (0.65) | HRH1SLC6A4SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL2242868 | 0.85 | PARP10 (0.55) | HRH1TSHRALOX12ALDH1A1PARP10 | |
| Bicarbonate SCHEMBL6205907 | 0.84 | HRH1 (0.55) | HRH1SLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL10231904 | 0.84 | NAAA (0.57) | HRH1TSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL28310871 | 0.84 | HRH1 (0.55) | HRH1TSHRSLC6A4SLC6A2SLC6A3 | |
| Ammonia Solution, Strong SCHEMBL8081694 | 0.83 | HRH1 (0.63) | HRH1SLC6A4SLC6A2SLC6A3SMN1; SMN2 | |
| Fluoride SCHEMBL28194548 | 0.83 | HRH1 (0.63) | HRH1SLC6A4SLC6A2SLC6A3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013048399-A1 | FLAME RETARDANT HALOGENATED PHENYL ETHERS | CHEMTURA CORPORATION (US) | 2013-04-04 | — | — | WO | disclosed |
| EP-0000506-A2 | Substituted phenyl O- or S- etherified cycloalkanols, a process for their preparation and their application as hypolipidemia, their esters with cyclopropanecarboxylic acids and the application of these esters as insecticides | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |