Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | DDX3X | O00571 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11502782 | 0.85 | MEN1 (0.48) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL27582546 | 0.82 | KMT2A (0.67) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL31185157 | 0.82 | SMN1; SMN2 (0.68) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL27964933 | 0.81 | KMT2A (0.69) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL3207627 | 0.81 | KMT2A (0.78) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL11502783 | 0.79 | NPC1 (0.44) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL5141415 | 0.79 | MEN1 (0.75) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL10692848 | 0.78 | KMT2A (0.66) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL1047211 | 0.78 | MEN1 (1.00) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL20474540 | 0.78 | KMT2A (0.60) | KMT2AMEN1MAPTPOLBDDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165365-A | ANTIALLERGENS ESPECIALLY FOR ASTHMA | SMITHKLINE CORPORATION (US) | 1979-08-21 | — | — | US | disclosed |