Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 1.00 |
| ▸ | DDX3X | O00571 | 2/20 | 1.00 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | BAZ1A | Q9NRL2 | 3/20 | 0.73 |
| ▸ | CA12 | O43570 | 2/20 | 0.73 |
| ▸ | CA1 | P00915 | 2/20 | 0.73 |
| ▸ | CA2 | P00918 | 2/20 | 0.73 |
| ▸ | CA9 | Q16790 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | CA5A | P35218 | 1/20 | 0.73 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17084065 | 0.98 | MEN1 (0.96) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL6129390 | 0.95 | MEN1 (0.90) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL4554987 | 0.91 | MEN1 (0.82) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL22092648 | 0.91 | MAPT (0.82) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL29494959 | 0.91 | MAPT (0.82) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL15507203 | 0.91 | MEN1 (0.82) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL10069069 | 0.91 | KMT2A (0.82) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL29494984 | 0.91 | MEN1 (0.82) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL12728640 | 0.90 | MEN1 (0.81) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL14336428 | 0.90 | KMT2A (0.81) | MEN1KMT2AMAPTHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212020-B1 | IMPRINTED POLYMERS WITH AFFINITY FOR PHOSPHORYLATED PEPTIDES AND PROTEINS | SELLERGREN BOERJE (SE) | 2018-07-04 | — | — | EP | disclosed |
| US-9932300-B2 | N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-04-03 | — | — | US | disclosed |
| US-20160318857-A1 | N,N'-Diarylurea Compounds and N,N'-Diarylthiourea Compounds as Inhibitors of Translation Initiation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2016-11-03 | — | — | US | disclosed |
| US-9421211-B2 | N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-08-23 | — | — | US | disclosed |
| US-9329186-B2 | Imprinted polymers with affinity for phosphorylated peptides and proteins | MIP TECHNOLOGIES AB (SE) | 2016-05-03 | — | — | US | disclosed |
| US-20150297694-A1 | CANCER DIAGNOSTIC AND THERAPEUTIC METHOD TARGETING MOLECULES EXPRESSED IN CANCER STEM CELLS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20120202814-A1 | COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2012-08-09 | — | — | US | disclosed |
| US-20120202814-A1 | COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2012-08-09 | — | — | US | disclosed |
| US-20120115915-A1 | N,N'-DIARYLUREA COMPOUNDS AND N,N'-DIARYLTHIOUREA COMPOUNDS AS INHIBITORS OF TRANSLATION INITIATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-05-10 | — | — | US | disclosed |
| WO-2011039735-A2 | COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2011-04-07 | — | — | WO | disclosed |
| EP-1250315-B1 | FUNCTIONAL MONOMERS FOR MOLECULAR RECOGNITION AND CATALYSIS | MIP TECHNOLOGIES AB (SE) | 2009-04-15 | — | — | EP | disclosed |
| EP-1927604-A1 | Functional monomers for molecular recognition and catalysis | MIP Technologies AB (SE) | 2008-06-04 | — | — | EP | disclosed |
| US-7332553-B2 | Functional monomers for molecular recognition and catalysis | MIP TECHNOLOGIES AB (SE) | 2008-02-19 | — | — | US | disclosed |
| US-20070106041-A1 | Functional monomers for molecular recognition and catalysis | MIP TECHNOLOGIES AB (SE) | 2007-05-10 | — | — | US | disclosed |
| US-7208557-B2 | Functional monomers for molecular recognition and catalysis | MIP TECHNOLOGIES AB (SE) | 2007-04-24 | — | — | US | disclosed |
| US-20050159570-A1 | Functional monomers for molecular recognition and catalysis | MIP TECHNOLOGIES AB, RESEARCH PARK IDEON (SE) | 2005-07-21 | — | — | US | disclosed |
| US-6870021-B2 | Functional monomers for molecular recognition and catalysis | MIP TECHNOLOGIES AB (SE) | 2005-03-22 | — | — | US | disclosed |
| US-20030166798-A1 | Functional monomers for molecular recognition and catalysis | MIP TECHNOLOGIES AB (SE) | 2003-09-04 | — | — | US | disclosed |
| EP-1250315-A1 | FUNCTIONAL MONOMERS FOR MOLECULAR RECOGNITION AND CATALYSIS | MIP Technologies AB (SE) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001055095-A1 | FUNCTIONAL MONOMERS FOR MOLECULAR RECOGNITION AND CATALYSIS | MIP TECHNOLOGIES AB (SE) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150297694-A1 | CANCER DIAGNOSTIC AND THERAPEUTIC METHOD TARGETING MOLECULES EXPRESSED IN CANCER STEM CELLS | DDX3X, DDX1, DDX24 | MEN1 2337/4885KMT2A 2830/4885MAPT 4498/4885 |
| US-20160318857-A1 | N,N'-Diarylurea Compounds and N,N'-Diarylthiourea Compounds as Inhibitors of Translation Initiation | NSUN2, EIF2AK2, RNGTT | MEN1 2936/4885KMT2A 761/4885MAPT 1631/4885 |
| US-20070106041-A1 | Functional monomers for molecular recognition and catalysis | PCNA, MUS81, PNMT | MEN1 2193/4885KMT2A 932/4885MAPT 2581/4885 |
| US-20120202814-A1 | COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF | DDX3X, DDX21, DDX39B | MEN1 1855/4885KMT2A 2610/4885MAPT 4074/4885 |
| US-20120115915-A1 | N,N'-DIARYLUREA COMPOUNDS AND N,N'-DIARYLTHIOUREA COMPOUNDS AS INHIBITORS OF TRANSLATION INITIATION | NSUN2, EIF2AK2, RNGTT | MEN1 2936/4885KMT2A 761/4885MAPT 1631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.