SCHEMBL11503545

SCHEMBL11503545

O=S(=O)(OCc1ccccc1)S(=O)(=O)Oc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.55
CA9 Q16790 7/20 0.55
CA1 P00915 6/20 0.55
KMT2A Q03164 1/20 0.53
PPARG P37231 1/20 0.43
AR P10275 4/20 0.42
CA12 O43570 2/20 0.42
CA4 P22748 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
TSHR P16473 1/20 0.41
PGR P06401 1/20 0.40
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HTT P42858 1/20 0.39
IDO1 P14902 1/20 0.39
STS P08842 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28624040 0.88 CA2 (0.68) CA2CA9CA1KMT2AAR
SCHEMBL10600073 0.81 CA2 (0.64) CA2CA9CA1KMT2APPARG
SCHEMBL9861791 0.79 CA2 (0.53) CA2CA9CA1KMT2APPARG
SCHEMBL31147821 0.79 CA2 (0.61) CA2CA9CA1KMT2APPARG
SCHEMBL1674292 0.79 CA2 (0.61) CA2CA9CA1KMT2APPARG
SCHEMBL1674247 0.79 CA2 (0.61) CA2CA9CA1KMT2APPARG
SCHEMBL27702475 0.76 CA2 (0.59) CA2CA9CA1KMT2AAR
SCHEMBL561014 0.74 CA2 (0.68) CA2CA9CA1KMT2ACA12
SCHEMBL3970940 0.74 CA1 (0.42) CA2CA9CA1KMT2APPARG
Ether SCHEMBL4275388 0.74 CA2 (0.47) CA2CA9CA1KMT2APPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4138570-A METHINE DYE BAYER AKTIENGESELLSCHAFT (DE) 1979-02-06 US claimed