Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.64 |
| ▸ | PGR | P06401 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | TNF | P01375 | 1/20 | 0.64 |
| ▸ | IL6 | P05231 | 1/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | GLUL | P15104 | 1/20 | 0.64 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594076 | 0.87 | HIF1A (0.52) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL978964 | 0.86 | NR3C1 (0.74) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Prednisolone Hemisuccinate SCHEMBL7155955 | 0.86 | HIF1A (0.84) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL4351238 | 0.85 | HIF1A (0.73) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Prednisolone Hemisuccinate SCHEMBL25138782 | 0.85 | HIF1A (0.85) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Prednisolone Hemisuccinate SCHEMBL13026153 | 0.85 | HIF1A (0.85) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Prednisolone Hemisuccinate SCHEMBL945987 | 0.85 | HIF1A (0.85) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Prednisolone Hemisuccinate SCHEMBL16009511 | 0.85 | HIF1A (0.85) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Prednisolone Hemisuccinate SCHEMBL12540510 | 0.85 | HIF1A (0.85) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Prednisolone Hemisuccinate SCHEMBL139689 | 0.85 | HIF1A (0.85) | NR3C1HIF1APGRHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178361-A | Sustained release pharmaceutical composition | UNION CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |