Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29785641 | 0.68 | MAOA (0.77) | MAOAMAOBLMNAMAPTALDH1A1 | |
| SCHEMBL275526 | 0.68 | MAOA (0.77) | MAOAMAOBLMNAMAPTALDH1A1 | |
| SCHEMBL2470956 | 0.68 | MAOA (0.77) | MAOAMAOBLMNAMAPTALDH1A1 | |
| SCHEMBL2557888 | 0.66 | MAOA (0.74) | MAOAMAOBLMNAMAPTALDH1A1 | |
| Benzene SCHEMBL10803509 | 0.66 | MAOA (0.82) | MAOAMAOBLMNAMAPTALDH1A1 | |
| SCHEMBL10884662 | 0.62 | MAOA (0.47) | MAOAMAOBLMNAMAPTALDH1A1 | |
| SCHEMBL28552825 | 0.61 | — | — | |
| SCHEMBL7159155 | 0.61 | MAOA (0.65) | MAOAMAOBLMNAMAPTALDH1A1 | |
| SCHEMBL13997489 | 0.61 | — | — | |
| SCHEMBL9403920 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138396-A | Pyridyl-azo-indolyl cationic dyes | CIBA-GEIGY CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |