Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 5/20 | 0.51 |
| ▸ | LRAT | O95237 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11505190 | 1.00 | GJB2 (0.51) | GJB2LRATGBA1CA1CA2 | |
| SCHEMBL11505181 | 0.90 | CA1 (0.49) | GJB2LRATCA1CA2CA9 | |
| SCHEMBL11505179 | 0.90 | CA1 (0.49) | GJB2LRATCA1CA2CA9 | |
| SCHEMBL22543403 | 0.89 | GJB2 (0.54) | GJB2LRATGBA1MAPK1 | |
| SCHEMBL19079099 | 0.89 | GJB2 (0.54) | GJB2LRATGBA1MAPK1 | |
| SCHEMBL18965292 | 0.88 | MAPK1 (0.53) | GJB2GBA1CA1CA2CA9 | |
| SCHEMBL11505524 | 0.88 | MAPK1 (0.53) | GJB2GBA1CA1CA2CA9 | |
| SCHEMBL11505522 | 0.88 | MAPK1 (0.53) | GJB2GBA1CA1CA2CA9 | |
| SCHEMBL18974160 | 0.88 | MAPK1 (0.53) | GJB2GBA1CA1CA2CA9 | |
| SCHEMBL18357371 | 0.88 | MAPK1 (0.53) | GJB2GBA1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156777-A | FROM AN AMINO-GLUCOPYRANOSE AND O-NITRO OR -CYANO-PHENYL N-SUBSTITUTED-N-NITROSOCARBAMATE; ANTITUMOR AGENTS | TOKYO TANABE COMPANY, LIMITED (JP) | 1979-05-29 | — | — | US | disclosed |