Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772360 | 0.80 | PDGFRB (0.77) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL32667946 | 0.80 | PDGFRB (0.77) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL27659350 | 0.79 | NPC1 (0.65) | PIK3CAKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL15968103 | 0.79 | CYP1A2 (0.56) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL2198777 | 0.79 | PDGFRB (0.60) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL29375329 | 0.79 | CYP1A2 (0.56) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL30547072 | 0.79 | PDGFRB (0.60) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL32691828 | 0.79 | PDGFRB (0.60) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL2624503 | 0.79 | PDGFRB (0.54) | PDGFRBPDGFRACYP2A6BIRC5CA12 | |
| SCHEMBL29064903 | 0.78 | PDGFRB (0.50) | PDGFRBPDGFRACYP2A6BIRC5CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187881-B | One kind has the compound, preparation method and application of 3- (2- hydroxy phenyl) quinoline structure unit | 河南大学 | 2019-04-23 | — | — | CN | claimed |
| CN-107714304-A | A kind of paper diaper with urine detection function and preparation method thereof | 上海速创诊断产品有限公司 | 2018-02-23 | — | — | CN | claimed |
| CN-106645676-A | Multi-term urine analysis test paper and preparation method thereof | 重庆普西医疗设备有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-104697993-A | Urine data acquiring device and application method thereof | WU YOUCAI | 2015-06-10 | — | — | CN | claimed |
| CN-104622648-A | Digital infant training pant | WU YOUCAI | 2015-05-20 | — | — | CN | claimed |
| CN-104622646-A | Digital infant urine isolation pad | WU YOUCAI | 2015-05-20 | — | — | CN | claimed |
| CN-104622647-A | Digital infant diaper | WU YOUCAI | 2015-05-20 | — | — | CN | claimed |
| CN-209059682-U | A kind of paper diaper with urine detection function | 上海速创诊断产品有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-106187881-B | One kind has the compound, preparation method and application of 3- (2- hydroxy phenyl) quinoline structure unit | 河南大学 | 2019-04-23 | — | — | CN | disclosed |
| CN-106187881-B | One kind has the compound, preparation method and application of 3- (2- hydroxy phenyl) quinoline structure unit | 河南大学 | 2019-04-23 | — | — | CN | disclosed |
| CN-107714304-A | A kind of paper diaper with urine detection function and preparation method thereof | 上海速创诊断产品有限公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-105636953-B | 1,4 dibasic pyridyl derivatives and its purposes for treating the illness related to SMN shortages | 诺华股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-106645676-A | Multi-term urine analysis test paper and preparation method thereof | 重庆普西医疗设备有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-201327492-Y | Multi-term urine analysis test paper | YANTAI BIOWAY BIOTECH CO LTD (CN) | 2009-10-14 | — | — | CN | disclosed |
| EP-1496896-A4 | INHIBITORS OF AKT ACTIVITY | MERCK & CO INC (US) | 2007-10-31 | — | — | EP | disclosed |
| CN-1993326-A | Heterocyclic acetophenone potentiators of metabotropic glutamate receptors | MERCK & CO INC (US) | 2007-07-04 | — | — | CN | disclosed |
| US-7223738-B2 | Inhibitors of Akt activity | MERCK & CO., INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-20050222155-A1 | Inhibitors of akt activity | MERCK SHARP & DOHME CORP. | 2005-10-06 | — | — | US | disclosed |
| EP-1496896-A1 | INHIBITORS OF AKT ACTIVITY | Merck & Co., Inc. (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003086394-A1 | INHIBITORS OF AKT ACTIVITY | MERCK & CO., INC. (US) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222155-A1 | Inhibitors of akt activity | AKT1, AKT2, AKT3 | PDGFRB 1134/4885PDGFRA 1412/4885CYP2A6 4559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.