SCHEMBL11508366

SCHEMBL11508366

c1ccc2c(c1)COCCOCCOCCOCCOC2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
CRHBP P24387 2/20 0.48
CRHR2 Q13324 2/20 0.48
HTT P42858 1/20 0.48
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
TSHR P16473 1/20 0.36
TTR P02766 1/20 0.35
ITGB2 P05107 1/20 0.35
ICAM1 P05362 1/20 0.35
ITGAL P20701 1/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
GAA P10253 2/20 0.34
CYP1A2 P05177 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11227471 1.00 LMNA (0.48) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11505348 1.00 LMNA (0.48) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11217888 1.00 LMNA (0.48) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11505102 1.00 LMNA (0.48) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11505083 1.00 LMNA (0.48) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11505050 1.00 LMNA (0.48) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11505205 1.00 LMNA (0.48) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL11505396 1.00 LMNA (0.48) LMNASMN1; SMN2CRHBPCRHR2HTT
SCHEMBL29471383 0.84
SCHEMBL59871 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4152335-A CROWN COMPOUNDS, NONHYGROSCOPIC SHELL OIL COMPANY (US) 1979-05-01 US claimed
US-4175093-A REACTING AN AROMATIC ALDEHYDE AND AN ACYL HALIDE WITH A CYANIDE, ADDING 1A CARBONATES OR HYDROXIDES TO RESTART SHELL OIL COMPANY (US) 1979-11-20 US disclosed
US-4175094-A REACTING AN AROMATIC ALDEHYDE AND AN ACID ANHYDRIDE SHELL OIL COMPANY (US) 1979-11-20 US disclosed
US-4152335-A CROWN COMPOUNDS, NONHYGROSCOPIC SHELL OIL COMPANY (US) 1979-05-01 US disclosed
US-4110363-A FROM AN ALDEHYDE, ACID HALIDE AND CYANIDE, MACROCYCLIC POLYETHER CATALYST SHELL OIL COMPANY (US) 1978-08-29 US disclosed
US-4110360-A FROM AN ALDEHYDE, ACID HALIDE AND CYANIDE SHELL OIL COMPANY (US) 1978-08-29 US disclosed