SCHEMBL11508709

SCHEMBL11508709

CCCOC(=O)C(C(=O)OCCC)=C(C(=O)OCCC)C(=O)OCCC

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HCAR2 Q8TDS4 1/20 0.44
ALDH1A1 P00352 6/20 0.43
TSHR P16473 4/20 0.41
LMNA P02545 3/20 0.41
ESR1 P03372 1/20 0.40
CHRM1 P11229 1/20 0.40
SLC6A2 P23975 1/20 0.40
KDR P35968 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
THRB P10828 1/20 0.38
ATM Q13315 1/20 0.37
NAAA Q02083 1/20 0.36
DGKA P23743 1/20 0.36
KDM4E B2RXH2 1/20 0.35
GLA P06280 1/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL138475 0.88 HCAR2 (0.48) GAASMN1; SMN2HCAR2ALDH1A1TSHR
Water SCHEMBL27557216 0.85 HCAR2 (0.46) GAASMN1; SMN2HCAR2ALDH1A1TSHR
SCHEMBL11510299 0.83 ALDH1A1 (0.61) SMN1; SMN2HCAR2ALDH1A1TSHRLMNA
SCHEMBL15913676 0.83 GAA (0.40) GAASMN1; SMN2HCAR2ALDH1A1TSHR
SCHEMBL16045173 0.82 HCAR2 (0.44) GAASMN1; SMN2HCAR2ALDH1A1TSHR
SCHEMBL10928182 0.81 ALDH1A1 (0.42) GAASMN1; SMN2HCAR2ALDH1A1TSHR
SCHEMBL15913473 0.81 GAA (0.39) GAASMN1; SMN2HCAR2ALDH1A1TSHR
SCHEMBL15913461 0.81 GAA (0.39) GAASMN1; SMN2HCAR2ALDH1A1TSHR
SCHEMBL4679321 0.80
SCHEMBL106813 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4132611-A Addition of organic electrophiles to carbon acids via catalysis by electrogenerated bases MONSANTO COMPANY (US) 1979-01-02 US disclosed
US-4072583-A Electrolytic carboxylation of carbon acids via electrogenerated bases MONSANTO COMPANY (US) 1978-02-07 US disclosed