Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.64 |
| ▸ | BCHE | P06276 | 7/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38666183 | 0.89 | ACHE (0.61) | ACHEBCHEFAAHALDH1A1 | |
| SCHEMBL1874668 | 0.89 | ACHE (0.61) | ACHEBCHEFAAHALDH1A1 | |
| SCHEMBL30519844 | 0.87 | ACHE (0.62) | ACHEBCHECYP1A2FAAHALDH1A1 | |
| SCHEMBL5933894 | 0.87 | ACHE (0.62) | ACHEBCHECYP1A2FAAHALDH1A1 | |
| SCHEMBL6738148 | 0.86 | ACHE (0.55) | ACHEBCHECYP1A2FAAHALDH1A1 | |
| SCHEMBL121183 | 0.86 | ACHE (0.55) | ACHEBCHECYP1A2FAAHALDH1A1 | |
| SCHEMBL29429135 | 0.86 | ACHE (0.55) | ACHEBCHECYP1A2FAAHALDH1A1 | |
| SCHEMBL121182 | 0.86 | ACHE (0.55) | ACHEBCHECYP1A2FAAHALDH1A1 | |
| SCHEMBL29546796 | 0.86 | ACHE (0.55) | ACHEBCHECYP1A2FAAHALDH1A1 | |
| SCHEMBL5933261 | 0.84 | ACHE (0.71) | ACHEBCHEFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172146-A | Substituted phenyl derivatives | CIBA-GEIGY CORPORATION (US) | 1979-10-23 | — | — | US | disclosed |
| US-4153604-A | INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |
| US-4069344-A | INSECTICIDAL SUBSTITUTED PHENYL DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1978-01-17 | — | — | US | disclosed |
| US-4067972-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4058604-A | OR ACARICIDALLY ACTIVE SUBSTANCES | CIBA-GEIGY AG (CH) | 1977-11-15 | — | — | US | disclosed |
| US-4035488-A | Insecticidal and acaricidal substituted phenyl thiophosphoric acid esters | CIBA-GEIGY CORPORATION (US) | 1977-07-12 | — | — | US | disclosed |
| US-4017563-A | INSECTICIDES, REDUCED TOXICITY TO MAMMALS | CIBA-GEIGY AG (CH) | 1977-04-12 | — | — | US | disclosed |
| US-4003964-A | ACARICIDES, INSECTICIDES, NEMATOCIDES | CIBA-GEIGY AG (CH) | 1977-01-18 | — | — | US | disclosed |
| US-3998855-A | INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |
| US-3991140-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1976-11-09 | — | — | US | disclosed |
| US-3956306-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
| US-3948940-A | Pesticidal phthalimido phosphorous ester compounds | CIBA-GEIGY CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |
| US-3941829-A | PESTICIDE | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |
| US-3940412-A | 2,4,5-Trichloro- and 2,4,5-tribromoimidazole derivatives and pesticidal compositions containing them | CIBA-GEIGY AG (CH) | 1976-02-24 | — | — | US | disclosed |
| US-3938986-A | ISOPROPYL N-PHENYLCARBAMATE OR ISOPROPYL N-(3-CHLOROPHENYL)CARBAMATE AND 4-CHLOROPHENYL N-METHYLCARBAMATE | PPG INDUSTRIES, INC. (US) | 1976-02-17 | — | — | US | disclosed |
| US-3935224-A | 4H-Pyrido[3,2a]-1,3,2-dioxophosphorane derivatives | CIBA-GEIGY CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |
| US-3934010-A | MITICIDE | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933945-A | O-ethyl-S-(n)propyl-S-diallylcarbmoylmethyldithiophosphate | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
| US-3932629-A | Triazolyl phosphorus esters as pesticides | CIBA-GEIGY CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
| US-3932630-A | Triazolyl phosphorus esters as pesticides | CIBA-GEIGY CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |