Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.61 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.46 |
| ▸ | HNF4A | P41235 | 2/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30059662 | 0.80 | MAOB (1.00) | MAOBMAOAADORA2B | |
| SCHEMBL1253672 | 0.80 | MAOB (1.00) | MAOBMAOAADORA2B | |
| SCHEMBL2403654 | 0.80 | TGFBR1 (0.57) | MAOBPTPN1PTPN2TBK1 | |
| SCHEMBL6720384 | 0.78 | MAOB (0.61) | MAOBMAOAACHEALDH1A1 | |
| SCHEMBL6720376 | 0.78 | MAOB (0.61) | MAOBMAOAADORA2BHNF4AACHE | |
| SCHEMBL28990301 | 0.78 | PTPN1 (0.64) | MAOBPTPN1PTPN2TBK1ALDH1A1 | |
| SCHEMBL4576015 | 0.78 | MAOB (0.61) | MAOBPTPN1MAOAADORA2BUSP2 | |
| SCHEMBL11513004 | 0.78 | MAOB (0.67) | MAOBMAOAUSP2ALDH1A1TSHR | |
| SCHEMBL31723115 | 0.78 | MAOB (0.61) | MAOBPTPN1MAOAALDH1A1 | |
| SCHEMBL3344909 | 0.78 | MAOB (0.61) | MAOBPTPN1TBK1MAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159268-A | ANTIBIOTICS, MICROBIOCIDES | AMERICAN CYANAMID COMPANY (US) | 1979-06-26 | — | — | US | disclosed |