SCHEMBL11510271

SCHEMBL11510271

CCCCCCOC(=O)N(Cl)Cl

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.55
EPHX1 P07099 1/20 0.52
TSHR P16473 3/20 0.50
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
HCAR2 Q8TDS4 1/20 0.47
RAD52 P43351 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
FAAH O00519 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
ACHE P22303 6/20 0.46
DGKA P23743 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11510270 0.89 TSHR (0.46) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL11024623 0.86 NAAA (0.53) NAAAEPHX1TSHRCA12CA1
SCHEMBL28221891 0.82
SCHEMBL8372851 0.81 NAAA (0.57) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL27915971 0.81 NAAA (0.57) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL5708956 0.79 NAAA (0.55) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL14759112 0.79 NAAA (0.55) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL11051780 0.79 NAAA (0.55) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL1502595 0.79 NAAA (0.55) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL5556965 0.79 NAAA (0.55) NAAAEPHX1TSHRHCAR2RAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4177289-A FUNGICIDES, HERBICIDES, BACTERICIDES EXXON RESEARCH & ENGINEERING CO. (US) 1979-12-04 US disclosed
US-4171449-A Addition of N,N-dichloro-N-acyl compounds to conjugated dienes and bis-N-chlorocrotyl carbamate products therefrom EXXON RESEARCH & ENGINEERING CO. (US) 1979-10-16 US disclosed
US-4170608-A REDUCTION, PESTICIDES EXXON RESEARCH & ENGINEERING CO. (US) 1979-10-09 US disclosed
US-4146557-A CHLORINATION, DECHLORINATION, ALKYLATION EXXON RESEARCH & ENGINEERING CO. (US) 1979-03-27 US disclosed