Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31478745 | 0.89 | MAPT (0.60) | MAPTTDP1MEN1KMT2AIDO1 | |
| SCHEMBL855529 | 0.86 | MAPT (0.50) | MAPTTDP1MEN1KMT2ACNR1 | |
| SCHEMBL5537374 | 0.85 | MAPT (0.49) | MAPTTDP1MEN1KMT2ACNR1 | |
| SCHEMBL11512030 | 0.84 | MEN1 (0.53) | MAPTTDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL11512272 | 0.83 | MAPT (0.56) | MAPTTDP1MEN1KMT2AIDO1 | |
| SCHEMBL11231501 | 0.82 | CA1 (0.57) | MAPTTDP1MEN1KMT2ACNR1 | |
| SCHEMBL10677205 | 0.80 | MAPT (0.51) | MAPTTDP1KMT2AIDO1HTT | |
| SCHEMBL11511314 | 0.80 | MEN1 (0.68) | MAPTMEN1KMT2ACNR1CYP1A2 | |
| SCHEMBL6212543 | 0.80 | P2RX1 (0.46) | MAPTTDP1MEN1KMT2ACNR1 | |
| SCHEMBL11512006 | 0.79 | MEN1 (0.47) | MAPTTDP1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |