SCHEMBL31478745

SCHEMBL31478745

Clc1ccc(CNc2ccccc2)c(Cl)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.60
ALDH1A1 P00352 3/20 0.60
NCOA3 Q9Y6Q9 2/20 0.60
ALOX12 P18054 1/20 0.60
PPARG P37231 1/20 0.60
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
PKM P14618 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
LMNA P02545 1/20 0.54
KDM1A O60341 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
MAOB P27338 4/20 0.50
SIGMAR1 Q99720 1/20 0.50
MAOA P21397 1/20 0.50
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 2/20 0.49
CYP2D6 P10635 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11510338 0.89 MAPT (0.57) MAPTALDH1A1NCOA3ALOX12PPARG
SCHEMBL11512272 0.87 MAPT (0.56) MAPTALDH1A1NCOA3ALOX12PPARG
SCHEMBL30339804 0.82 L3MBTL1 (0.50) MAPTALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL5537374 0.82 MAPT (0.49) MAPTALDH1A1NCOA3ALOX12PPARG
SCHEMBL30339822 0.82 ALOX12 (0.49) MAPTALDH1A1NCOA3ALOX12PPARG
SCHEMBL30520433 0.80 MEN1 (0.53) MAPTALDH1A1NCOA3ALOX12PPARG
SCHEMBL19197930 0.80 MEN1 (0.53) MAPTALDH1A1NCOA3ALOX12PPARG
SCHEMBL7988500 0.80 RAB9A (0.65) MAPTALOX12MEN1KMT2AL3MBTL1
SCHEMBL11513239 0.80 LMNA (0.49) MAPTALDH1A1NCOA3ALOX12PPARG
SCHEMBL855529 0.80 MAPT (0.50) MAPTALDH1A1NCOA3ALOX12PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798177-A In the sulfenamide Process for the preparation of intermediates 宁夏格瑞精细化工有限公司 2025-04-11 CN disclosed