Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061326 | 0.86 | LMNA (0.44) | LMNATP53MDM2 | |
| SCHEMBL25644310 | 0.83 | LMNA (0.42) | LMNATP53MDM2 | |
| SCHEMBL15898460 | 0.81 | LMNA (0.44) | LMNATP53MDM2 | |
| SCHEMBL2521070 | 0.81 | LMNA (0.44) | LMNATP53MDM2 | |
| SCHEMBL24106548 | 0.81 | LMNA (0.41) | LMNATP53MDM2 | |
| SCHEMBL15894719 | 0.81 | LMNA (0.42) | LMNA | |
| SCHEMBL24356067 | 0.75 | LMNA (0.34) | LMNA | |
| SCHEMBL24356068 | 0.75 | LMNA (0.34) | LMNA | |
| SCHEMBL24404203 | 0.75 | LMNA (0.40) | LMNATP53MDM2 | |
| SCHEMBL7745388 | 0.75 | F2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507692-B2 | Ester compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20120309803-A1 | ESTER COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-06 | — | — | US | disclosed |
| US-4176189-A | Insecticidal and acaricidal hydantoin N-methylol esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309803-A1 | ESTER COMPOUND AND USE THEREOF | CYP51A1, CYP4A11, CES1 | LMNA 1860/4885TP53 4712/4885MDM2 4285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.